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Schematic figure of the most populated GH5 binding modes on the nucleosome. The dominant binding position (left) on the nucleosome and LH orientation (orange, K69site; green, R42site; grey, K59site) found for 8 nucleosome conformations with a distance between L-DNA ends less than 65 Å. The three most open nucleosome conformations with a L-DNA distance more than 65 Å attract LH to L-DNA2 (right). However, two different LH orientations contribute to the most populated docked solutions.
