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Interactions of the IRES RNA with the ribosome. (a) Molecular interactions of the CrPV IRES (magenta ribbon) with ribosomal proteins S5 (orange) and S25 (red). (b) A close-up of the interaction partners docked into the cryo-EM density (grey mesh) of the yeast 80S•CrPV complex [(34); M. Muhs and C. M. T. Spahn, unpublished data].
