Table 1.
Pretreatment Demographic and Clinical Measures1
| Placebo | Sertraline | Significance Level4 | |||||
|---|---|---|---|---|---|---|---|
| EOAs2 (n=25) | LOAs3 (n=46) | EOAs2 (n=21) | LOAs3 (n=42) | Treatment | Age of Onset | Interaction | |
| Demographic Features | |||||||
| Sex (% male) | 84.0 | 78.3 | 95.2 | 73.8 | 0.92 | 0.07 | 0.19 |
| Race (% white) | 100 | 89.1 | 90.5 | 90.5 | 0.60 | 0.24 | 0.13 |
| Age (years) | 42.2 (10.8) | 50.1 (7.5) | 44.1 (10.9) | 49.5 (9.3) | 0.81 | <0.001 | 0.45 |
| Education (years) | 14.0 (2.1) | 15.2 (2.4) | 14.4 (2.5) | 14.1 (2.0) | 0.13 | 0.22 | 0.07 |
| Clinical Features | |||||||
| Number of DSM-IV Criteria for AD5 | 6.2 (1.1) | 5.7 (1.1) | 6.3 (0.7) | 6.0 (1.0) | 0.32 | 0.02 | 0.64 |
| Drinking Days (%) | 62.7 (28.6) | 71.4 (25.3) | 70.2 (22.6) | 66.0 (27.8) | 0.84 | 0.57 | 0.18 |
| Heavy Drinking Days (%) | 56.8 (30.0) | 61.2 (28.0) | 57.8 (31.6) | 50.6 (30.1) | 0.19 | 0.84 | 0.29 |
| Mean Drinks Per Day | 6.7 (4.1) | 6.1 (3.8) | 7.7 (5.9) | 6.0 (4.3) | 0.74 | 0.17 | 0.47 |
| Short Index of Problems Score | 23.4 (7.5) | 20.8 (8.6) | 24.1 (8.0) | 19.1 (9.2) | 0.53 | 0.02 | 0.42 |
| Lifetime Major Depression (%) | 20.0 | 23.9 | 28.6 | 14.3 | 0.62 | 0.53 | 0.21 |
| Beck Depression Inventory Score | 6.7 (5.7) | 6.4 (5.6) | 7.2 (5.8) | 5.5 (6.5) | 0.68 | 0.35 | 0.52 |
1
Mean (SD) or percentage;
2
EOAs: Early-Onset Alcoholics;
3
LOAs: Late-Onset Alcoholics;
4
F-test for continuous measures and χ2 test for categorical measures;
5
Current alcohol dependence