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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Horm Behav. 2011 May 20;60(2):226–232. doi: 10.1016/j.yhbeh.2011.05.005

Figure 2.

Figure 2

Effects of finasteride on the response to restraint

Ovariectomized rats were hormonally primed with 10 μg EB and injected 48 hr later with 50 μg progesterone (EP) or the sesame seed oil vehicle (EO). Two hr prior to injection with progesterone, rats were injected with finasteride (dissolved in propylene glycol) or the propylene glycol vehicle. Finasteride was administered s.c. at a dose of 50 mg/kg in a volume of 1 ml/kg body weight. N’s for EO-Vehicle, EP-Vehicle and EP-finasteride, respectively, were 7, 15 and 20. Four to six hr after progesterone, rats were pretested for sexual behavior, restrained for 5 min, and immediately tested for 15 consecutive min. Data are the mean ± S.E. L/M ratios for each of the test intervals. * Indicates significant differences from the pretest L/M ratio. ** Indicates significant differences between EO-Vehicle rats and those primed either with EB and progesterone or with EB and finasteride (all p≤0.05).