Table 1. Experimentally observed fractional neuron and astrocyte glucose uptake.
Reference |
Glucose uptake (%) |
Relative neuron:astrocyte uptake capacitya | System | |
---|---|---|---|---|
Neuron | Astrocyte | |||
Barros et al (2009) | 10 | 90 | 1.0:17.1 | Cerebellar slices |
Vega et al (2003) | 20 | 80 | 1.0:7.3 | Rat vagus nerve |
Nehlig et al (2004)b | 53 | 47 | 1.0:1.6 | Freely moving rats |
Zielke et al (2007) | 65 | 35 | 1.0:1.0 | Freely moving rats |
Qu et al (2000) | 70 | 30 | 1.0:0.8 | Anesthetized rats |
Hassel et al (1995) | 70 | 30 | 1.0:0.8 | Ex vivo |
These values take into account the different volume fractions of neurons (45%) and astrocytes (25%) in the cerebral cortex.
After normalization (error due to the experimental technique, it was 60% for neurons and 53% for astrocytes, which is >100%).