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Temporal progression of pupil reactivity and ICP in two patients; ICP in the top panels, pupil reactivity (NPi) in the lower panels, red for the right pupil and blue for the left pupil (see text for clinical information). Normal range of pupil reactivity is for NPi values between 3 and 5. The threshold between normal and abnormal pupil reactivity is indicated with a solid back horizontal line in the lower panels
