Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The life cycle of epigenome. Scheme representing major changes in epigenetic information as they occur during the mouse development. DNA demethylation proceeds in the male pronucleus of the zygote followed later by the erasure of polycomb (Pc) marks in the ICM of blastocyst. PGCs undergo erasure of both DNA methylation and polycomb marks at E11.5. 5mc, 5-methyl-cytosine.
