Table 2.

Thirteen genes regulated in common at 24 h after stroke in mice preconditioned with LPS, CpG, or brief ischemia

Symbol	Title	LPS + stroke 24 h		CpG + stroke 24 h		IP + stroke 24 h		Strokea 24 h
		Fold changeb	FDR-adjusted p value	Fold change	FDR-adjusted p value	Fold change	FDR-adjusted p value	Fold change	FDR-adjusted p value
Fcgr1	Fc receptor, IgG, high affinity I	3.06	2.8 × 10−9	3.03	2.3 × 10−9	2.36	1.3 × 10−5	1.85/1.77	0.0004/0.001
HGF	Hepatocyte growth factor	2.56	2.1 × 10−9	3.04	6.1 × 10−12	2.30	6.0 × 10−7	1.49/1.85	0.007/3.2 × 10−5
Ifit1	IFN-induced protein with tetratricopeptide repeats 1	3.04	0.0001	2.61	0.0009	2.85	0.001	1.39/1.28	0.32/0.45
Ifit3	IFN-induced protein with tetratricopeptide repeats 3	2.07	2.1 × 10−5	2.04	2.4 × 10−5	2.04	0.0001	1.54/1.40	0.01/0.05
Oasl2	2′-5′Oligoadenylate synthetase-like 2	2.47	0.0009	2.59	0.0004	2.55	0.002	1.24/1.19	0.51/0.58
Plscr2	Phospholipid scramblase 2	2.56	3.9 × 10−7	2.93	9.4 × 10−9	2.11	0.0001	1.32/1.45	0.15/0.04
Pycard	PYD and CARD domain containing	2.60	8.9 × 10−9	2.57	8.3 × 10−9	2.27	3.6 × 10−6	1.69/1.68	0.0007/0.0009
Pyhin1	Pyrin and HIN domain family, 1	2.66	3.9 × 10−6	2.52	9.4 × 10−6	2.17	0.0008	1.44/1.85	0.09/0.003
Viperin	Radical S-adenosyl methionine domain containing 2	3.82	4.2 × 10−6	3.02	0.0001	2.67	0.002	1.84/1.75	0.03/0.05
Rtp4	Receptor transporter protein 4	2.96	1.3 × 10−7	2.66	1.0 × 10−6	2.48	3.9 × 10−5	1.56/1.52	0.02/0.03
Trim30	Tripartite motif protein 30	2.50	2.5 × 10−6	2.43	3.9 × 10−6	2.09	0.0005	1.50/1.53	0.03/0.02
Usp18	Ubiquitin specific peptidase 18	2.93	0.0001	2.68	0.0003	3.40	8.7 × 10−5	1.35/1.16	0.34/0.6
Zbp1	Z-DNA binding protein 1	2.20	1.0 × 10−5	2.79	2.0 × 10−8	2.07	0.0002	1.57/1.66	0.01/0.003

^aNontreated stroke alone/saline-treated stroke.

^bFold change compared with untreated mice. Genes are considered significantly regulated if fold change > 2 and FDR-adjusted p < 0.01.