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. Author manuscript; available in PMC: 2012 Apr 15.
Published in final edited form as: Bioorg Med Chem. 2011 Mar 12;19(8):2557–2564. doi: 10.1016/j.bmc.2011.03.019

Table 3.

Quantified Binding Constants of the G3-MTX and free FA with FBP Measured by SPR

kon koff KD
G3-MTX 2.48E+04 9.76E-04 3.94E-08
FA 2.10+03 4.8E-02 2.29E-05