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. 2000 Dec;10(12):1979–1985. doi: 10.1101/gr.10.12.1979

Figure 1.

Figure 1

Human V1R-like sequences obtained by PCR using consensus rat V1R primers. (A) The predicted sequences of human PhH5 and PhH8 proteins combined with rat V1R sequences (Dulac and Axel 1995). The sequence alignment was performed using the PileUp program from the GCG package. The aminoacids of the rat sequences are numbered according to their complete sequences, and the aminoacids of the partial human sequences are arbitrarily numbered from 1 to 110. The predicted positions of transmembrane domains IV and V are indicated by horizontal lines. Aminoacids common to at least six of the nine sequences and including at least one human sequence are highlighted in grey. Stop codons are represented by asterisks. Insertions or deletions leading to frameshifts are indicated as vertical bars. (B) Identity dendrogram of sequences presented above using the PileUp program. Families (amino acid sequence identity or ASI > 40%) are marked by circled numbers and subfamilies (ASI > 60%) by squared letters. The percentage of ASI was estimated by pairwise sequence comparisons using the GAP program (GCG package) and is indicated along the bottom.