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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: J Thromb Haemost. 2011 May;9(5):1020–1028. doi: 10.1111/j.1538-7836.2011.04233.x

Figure 1.

Figure 1

‘In vitro’ transfusion model. Whole blood obtained from adult subjects (peripheral blood [PB]) or cord blood (CB) was separated into platelet-poor plasma (PPP), red blood cells (RBCs), and buffy coat (BC). The BC was allowed to rest and, after a soft spin, a platelet concentrate was generated from the supernatant. The pellet resulting from this spin was mixed with the PPP and RBCs from the first centrifugation to reconstitute platelet-depleted blood. PB-derived and CB-derived platelet concentrates were mixed with platelet-depleted CB or PB to mimic autologous and allogeneic transfusions (n = 7 per group). Plt, platelet; WBC, white blood cell; RC, red cells.