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Amino acid substitutions in Pvs230 of P. vivax populations used in this study. IVP and ICP are interspecies variable part and interspecies conserved part, respectively. Amino acid positions are numbered after the Sal-1 sequences. Country-specific amino acid changes are boxed. The category “Others” include Nicaragua, and Panama strains and two isolates from Solomon Islands. Amino acid substitutions with minor allele frequency of ≤0.5% are highlighted in grey.
