Table 1.

Assigned Protein Identification Using LC-MS/MS

Spot	p-value	Fold-change	Protein ID	ACC. No. (Swissprot)	Gene	Sequence coverage (%)	No. peptides identified	Mr/pI
9*	0.02	1.33	Annexin A2	P07355	ANXA2	38.6	13	38/7.56
			Ribose-phosphate pyrophosphokinase 1	P60891	PRPS1	15.1	4	35/6.56
			Voltage-dependent anion-selective channel protein 2	P45880	VDAC2	17.70	5	32/7.5
			Dual specificity mitogen-activated protein kinase kinase 6	P52564	MAP2K6	11.4	3	37/7.01
14*	0.04	1.40	Flotillin-1	O75955	FLOT1	62.3	23	47/7.08
			Alpha-enolase	P06733	ENO1	6.68	2	47/6.99
16*	0.04	-1.32	Cdc42-interacting protein 4	Q15462	TRIP10	50.6	22	69/5.55
			78 kDa glucose-regulated protein (GRP78)	P11021	HSPA5	47.6	32	72/5.01
			Collagen type IV alpha-3 binding protein	Q9Y5P4	COL4A3BP	20.7	9	71/5.29
			NADH-ubiquinone oxireductase 75 kDa subunit, mitochondrial	P28331	NDUFS1	13.2	8	79/5.42
			Stress-70 protein, mitochondrial	P38646	HSPA9	11.5	7	74/5.44
22*	0.04	-1.32	cDNA FLJ5299	A8K781	cDNA FLJ5299	47.0	17	47/5.11
			Keratin, type II cytoskeletal 8	P05787	KRT8	46.8	25	48/5.34
			Thioredoxin domain-containing protein 5	Q8NBS9	TXNDC5	27.3	11	48/5.37
			Actin, cytoplasmc 1	P60709	ACTB	26.4	9	42/5.29
			26S protease regulatory subunit 6B	P43686	PSMC4	22.7	9	47/5.09
			Uncharacterised protein KIAA0174 (ISTI homolog)	P53990	KIAA0174	14.6	5	40/5.22
			Eukaryotic initiation factor 4A-1	P60842	EIF4A1	16.0	5	46/5.32
			Hsc70-interacting protein	P50502	ST13	12.5	4	41/5.18
			Heterogenous nuclear ribonucleoprotein F	P52597	HNRNPF	19.3	4	46/5.38

^a Asterisk (*) denotes spots identified as containing a mixture of 2 or more proteins, or where protein isoforms cannot be distinguished based on peptides identified.

P-value and fold-change obtained based on normalised spot volume between control and IL11 treated group.