Table 1.

Statistical measures for the predicted two subtypes of Breast cancer*.

Disease subtypes (Disease subgroup)	Number of gene pairs with high topological similarity MHT(g, g') <θR)	Number of gene pairs with low topological similarity MHT(g, g') >θR)	P value#
Within subgroup 1	56	64	P1<0.0001
Within subgroup 2	333	570	P2<0.0001
Between subgroups 1 and 2	128	480

*: We assess the modularity level of the predicted disease subtypes by comparing topological similarity of gene pairs within each subgroup to gene pairs between the two subgroups.

#: The P value of disease subgroup 1 (P₁) and the P value of disease subgroup 2 (P₂) are calculated using the Fisher's Exact Test.