Table 3. Risk of POAG between GST genotypes.
| Genotype | Cases n (%) | Control n (%) | OR (IC 95) | p value* |
|---|---|---|---|---|
|
GSTM1 | ||||
|
GSTM1+ |
44 (50.6) |
58 (68.2) |
Ref. |
־ |
|
GSTM1- |
43 (49.4) |
27 (31.8) |
2.1 (1.13–3.9) |
0.018 |
|
GSTT1 | ||||
|
GSTT1+ |
72 (82.8) |
61 (71.8) |
Ref. |
־ |
|
GSTT1- |
15 (17.2) |
24 (28.2) |
0.53 (0.25–1.01) |
0.085 |
|
GSTP1 | ||||
| Ile/Ile |
44 (50.6) |
45 (52.9) |
Ref. |
־ |
| Ile/Val |
35 (40.2) |
34 (40) |
1.05 (0.56–2.0) |
0.873 |
| Val/Val |
08 (09.2) |
06 (07.1) |
1.36 (0.44–4.25) |
0.592 |
| Ile/Val or Val/Val |
43 (49.4) |
40 (47.1) |
1.01 (0.6–2.0) |
0.756 |
| Ile |
123 (71.0) |
124 (73.0) |
Ref. |
־ |
| Val | 51 (39.0) | 46 (27.0) | 1.12 (0.7–1.8) | 0.643 |
Reference groups: GSTM1+ (non-deleted), GSTT1+ (non-deleted) and GSTP1 wild-type allele. *χ2 test.