Table 4. Distribution of GST genotypes combined between cases and controls.
| Genotype combinations |
Groups |
|
|
|
|---|---|---|---|---|
| Cases n (%) | Controls n (%) | OR (IC 95) | p value* | |
|
GSTM1/GSTT1 | ||||
| M1+/T1+ |
36 (41.4) |
43 (50.6) |
Ref. |
־ |
| M1+/T1- |
8 (9.2) |
15 (17.6) |
0.64 (0.24–1.67) |
0.358 |
| M1-/T1+ |
36 (41.4) |
18 (21.2) |
2.4 (1.16–4.9) |
0.016 |
| M1-/T1- |
7 (8) |
9 (10.6) |
0.93 (0.31–2.74) |
0.894 |
|
GSTM1/GSTP1 | ||||
| M1+/Ile/Ile |
24 (27.6) |
28 (32.9) |
Ref. |
־ |
| M1+/ Ile/Val or Val/Val |
20 (23.0) |
30 (35.3) |
0.78 (0.35–1.7) |
0.53 |
| M1-/ Ile/Val or Val/Val |
23 (26.4) |
10 (11.8) |
2.7 (1.07–6.74) |
0.033 |
| M1-/Ile/Ile |
20 (23.0) |
17 (20) |
1.37 (0.6–3.2) |
0.463 |
|
GSTT1/GSTP1 | ||||
| T1+/Ile/Ile |
35 (40.2) |
34 (40.0) |
Ref. |
־ |
| T1+/ Ile/Val or Val/Val |
37 (42.5) |
27 (31.8) |
1.33 (0.67–2.64) |
0.412 |
| T1-/ Ile/Val or Val/Val |
6 (6.9) |
13 (15.3) |
0.45 (0.15–1.3) |
0.138 |
| T1-/Ile/Ile | 9 (10.3) | 11 (12.9) | 0.8 (0.29–2.16) | 0.652 |
Reference groups: GSTM1+ (non-deleted), GSTT1+ (non-deleted) and GSTP1 wild-type allele. *χ2 test.