Table 7. Risk alleles and MAF for the three SNPs of LOXL1 in different populations.
|
|
rs1048661 (G/T) |
rs3825942 (G/A) |
rs2165241 (T/C) |
|
|||
|---|---|---|---|---|---|---|---|
| Population | Risk allele | MAF | Risk allele | MAF | Risk allele | MAF | Reference |
| Iceland |
G |
0.349(T) |
G |
0.153 (A) |
T |
0.473 (T) |
[20] |
| Sweden |
G |
0.318 (T) |
G |
0.121 (A) |
T |
0.465 (C) |
|
| Austria |
G |
0.329 (T) |
G |
0.183 (A) |
NA |
NA |
[28] |
| United States |
G |
0.335 (T) |
G |
0.156 (A) |
T |
0.487 (T) |
[27] |
| United States |
G |
0.297 (T) |
G |
0.202 (A) |
T |
0.448 (T) |
[29] |
| United States |
G |
0.400 (T) |
G |
0.120 (A) |
NA |
NA |
[30] |
| United States |
G |
0.281 (T) |
G |
0.205 (A) |
T |
0.456 (T) |
[31] |
| Germany and Italy |
G |
0.348 (T) |
G |
0.149 (A) |
T |
0.488 (T) |
[32] |
| Australia |
G |
NA |
G |
NA |
NA |
NA |
[22] |
| refSNP (European) |
NA |
0.040 (T) |
NA |
0.172 (T) |
NA |
0.392 (T) |
NCBI Database |
| India |
* |
0.270 (T) |
G |
0.070 (A) |
NA |
NA |
[23] |
| Japan |
T |
0.450 (G) |
G |
0.147 (A) |
NA |
NA |
[33] |
| Japan |
T |
0.497 (G) |
G |
0.137 (A) |
C |
0.102 (T) |
[34] |
| Japan |
T |
0.460 (G) |
G |
0.143 (A) |
NA |
NA |
[35] |
| Japan |
T |
NA |
G |
NA |
NA |
NA |
[36] |
| Japan |
T |
0.493 (T) |
G |
0.123 (A) |
NA |
NA |
[37] |
| Japan |
T |
0.450 (T) |
G |
0.194 (A) |
C |
0.124 (T) |
[38] |
| Singapore (Chinese) |
* |
0.444 (G) |
G |
0.082 (A) |
NA |
NA |
[39] |
| China (Beijing) |
T |
0.484 (G) |
G |
0.104 (A) |
C |
0.100 (T) |
[25] |
| China (Xinjang Uygur) |
G |
0.188 (T) |
G |
0.047 (A) |
T |
0.244 (T) |
present study |
| China |
|
|
|
|
|
|
[40] |
| (Hong Kong) |
NA |
0.470 (G) |
NA |
0.124 (A) |
NA |
0.102 (T) |
|
| (Beijing) |
NA |
0.497 (G) |
NA |
0.135 (A) |
NA |
0.084 (T) |
|
| Asian (China) |
NA |
NA |
NA |
0.111 (T) |
NA |
0.067 (T) |
|
| Asian (Japan) | NA | 0.438 (G) | NA | 0.125 (T) | NA | 0.167 (T) | |
NA indicates not available. The asterisk indicates that no association was found. MAF indicates minor allele frequency.