Table 2. Number of newborns with TEP and BPR, per year and geographical region, in the period of 2000–2008 by Poisson distribution.

	Brazil				Northeast				Southeast				South
Year	TEP	Births	BPR	CI 95%	TEP	Births	BPR	CI 95%	TEP	Births	BPR	CI 95%	TEP	Births	BPR	CI 95%
2000	11	40104	2.74	1.40–4.90	-	-	-	-	6	12047	5.00	1.80–10.80	5	28057	1.80	0.60–4.20
2001	10	38742	2.50	1.20–4.70	0	5088	0.00	0.00–10.2	8	11876	6.74	2.90–13.30	2	21778	0.92	0.10–3.30
2002	10	40231	2.49	1.20–4.60	0	6617	0.00	0.00–7.8	8	12197	6.56	280–12.80	2	21417	0.93	0.10–3.40
2003	10	42061	2.38	1.10–4.40	0	10171	0.00	0.00–4.90	4	11466	3.50	0.90–8.90	6	20424	2.94	1.10–6.40
2004	11	42581	2.58	1.30–4.60	2	9733	2.10	0.20–7.40	5	11316	4.42	1.40–10.30	3	21532	1.40	0.30–4.10
2005	16	37518	4.26	2.40–6.90	7	10196	6.90	2.80–14.10	5	10909	4.60	1.50–10.70	5	16413	3.05	1.00–7.10
2006	15	38298	3.92	2.20–6.50	6	9341	6.42	2.30–14.00	4	13021	3.10	0.80–7.90	5	15936	3.24	1.00–7.30
2007	16	38281	4.18	2.40–6.80	2	8627	2.32	0.30–8.40	13	14658	8.90	4.70–13.20	1	14996	0.70	0.10–3.70
2008	10	34221	2.92	1.40–5.40	5	8920	5.60	1.80–13.10	3	13192	2.30	0.50–6.60	2	12109	1.65	0.20–6.00
Total	109	352037	3.10	2.50–3.70	22	68693	3.20	2.00–4.80	56	110682	5.10 *	3.80–6.80	31	172662	1.80 *	1.20–2.50

Footnote: TEP: thalidomide embryopathy phenotype; BPR: birth prevalence rate; CI 95%: confidence interval of 95%.

*p<0.05.

-: year without monitoring by ECLAMC. BPR per 10 thousand births.