|
NFKB genes (n = 10)
|
|
|
|
NFKB1
|
p50, p105 |
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
4q24 |
NM_003998 |
|
NFKB2
|
p52, p100 |
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 |
10q24 |
NM_002502 |
| REL |
C-Rel |
v-rel reticuloendotheliosis viral oncogene homolog |
2p13-p12 |
NM_002908 |
|
RELA
|
p65, NFKB3 |
v-rel reticuloendotheliosis viral oncogene homolog A (p65) |
11q13 |
NM_021975 |
| RELB |
I-REL |
v-rel reticuloendotheliosis viral oncogene homolog B |
19q13.32 |
NM_006509 |
|
CHUK
|
IκKα |
Conserved helix-loop-helix ubiquitous kinase |
10q24-q25 |
NM_001278 |
|
IKBKB
|
IκKβ |
Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
8p11.2 |
NM_001556 |
|
IKBKG
|
IκKγ, Nemo |
Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma |
Xq28 |
NM_003639 |
|
NFKBIA
|
IκBα |
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
14q13 |
NM_020529 |
|
NFKBIB
|
IκBβ |
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
19q13.1 |
NM_002503 |
|
Apoptosis (n = 12)
|
|
|
|
BCL2A1
|
BFL1/A1 |
Baculoviral IAP repeat-containing 2 |
15q24.3 |
NM_004049 |
|
GADD45B
|
|
Growth arrest and DNA-damage-inducible, beta |
19p13.3 |
NM_015675 |
|
TNFRSF10B
|
TRAILR2 |
Tumor necrosis factor receptor superfamily, member 10b |
8p22-p21 |
NM_003842 |
|
FASLG
|
TNFSF6 |
Fas ligand (TNF superfamily, member 6) |
1q23 |
NM_000639 |
|
BIRC4
|
XIAP |
Baculoviral IAP repeat-containing 4 |
Xq25 |
NM_001167 |
|
TNFAIP3
|
A20 |
Tumor necrosis factor, alpha-induced protein 3 |
6q23 |
NM_006290 |
|
TRAF2
|
|
TNF receptor-associated factor 2 |
9q34 |
NM_021138 |
|
IER3S
|
|
Immediate early response 3, large transcript |
6p21.3 |
NM_003897 |
|
IER3L
|
|
Immediate early response 3, short transcript |
6p21.3 |
NM_052815 |
|
BIRC2
|
c-IAP1 |
Baculoviral IAP repeat-containing 2 |
11q22 |
NM_001166 |
|
MCL1S
|
|
Myeloid cell leukemia sequence 1 (BCL2-related), short transcript |
1q21 |
NM_182763 |
|
MCL1L
|
|
Myeloid cell leukemia sequence 1 (BCL2-related), large transcript |
1q21 |
NM_021960 |
|
Immune response (n = 12)
|
|
IL1A
|
|
Interleukin 1, alpha |
2q14 |
NM_000575 |
|
IL1B
|
|
Interleukin 1, beta |
2q14 |
NM_000576 |
|
IL6
|
|
Interleukin 6 (interferon, beta 2) |
7p21 |
NM_000600 |
|
IL12B
|
|
Interleukin 12B (natural killer cell stimulatory factor 2) |
5q31.1-q33.1 |
NM_002187 |
|
CCL2
|
MCP-1 |
Chemokine (C-C motif) ligand 2 |
17q11.2-q21.1 |
NM_002982 |
|
TNFRSF11A
|
RANK |
Tumor necrosis factor receptor superfamily, member 11a, activator of NFKB |
18q22.1 |
NM_003839 |
|
TNFSF11
|
RANKL |
Tumor necrosis factor (ligand) superfamily, member 11 |
13q14 |
NM_003701 |
|
TNF
|
|
Tumor necrosis factor (TNF superfamily, member 2) |
6p21.3 |
NM_000594 |
|
TNFRSF1A
|
TNFR1 |
Tumor necrosis factor receptor superfamily, member 1A |
12p13.2 |
NM_001065 |
|
TNFRSF1B
|
TNFR2 |
Tumor necrosis factor receptor superfamily, member 1B |
1p36.3-p36.2 |
NM_001066 |
|
CD40
|
|
CD40 antigen (TNF receptor superfamily member 5) |
20q12-q13.1 |
NM_001250 |
|
CD40LG
|
|
CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome) |
Xq26 |
NM_000074 |
|
Cell Proliferation (n = 7)
|
|
CSF1
|
MCSF |
Colony stimulating factor 1 (macrophage) |
1p21-p13 |
NM_000757 |
|
CSF1R
|
|
Colony stimulating factor 1 receptor, v-fms oncogene homolog |
5q33-q35 |
NM_005211 |
|
CSF2
|
GMCSF |
Colony stimulating factor 2 (granulocyte-macrophage) |
5q31.1 |
NM_000758 |
|
CCND1
|
|
Cyclin D1 (PRAD1 : parathyroid adenomatosis 1) |
11q13 |
NM_053056 |
|
CCND2
|
|
Cyclin D2 |
12p13 |
NM_001759 |
|
CCND3
|
|
Cyclin D3 |
6p21.3 |
NM_001760 |
|
CCNG1
|
|
Cyclin G1 |
5q32-q34 |
NM_004060 |
|
Tumor progression (n = 9)
|
|
MMP9
|
|
Matrix metalloproteinase 9 (gelatinase B, 92kDa type IV collagenase) |
20q11.2-q13.1 |
NM_004994 |
|
MMP11
|
|
Matrix metalloproteinase 11 (stromelysin 3) |
22q11.23 |
NM_005931 |
|
PLAU
|
UPA |
Plasminogen activator, urokinase |
10q24 |
NM_002658 |
|
CXCR4
|
|
Chemokine (C-X-C motif) receptor 4 |
2q21 |
NM_003467 |
|
CXCL12
|
SDF1 |
Chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) |
10q11.1 |
NM_000609 |
|
ICAM1
|
|
Intercellular adhesion molecule 1 (CD54), human rhinovirus receptor |
19p13.3-p13.2 |
NM_000201 |
|
VCAM1
|
|
Vascular cell adhesion molecule 1 |
1p32-p31 |
NM_001078 |
|
SELE
|
ELAM1 |
Selectin E (endothelial adhesion molecule 1) |
1q22-q25 |
NM_000450 |
|
TNC
|
HXB |
Tenascin C (hexabrachion) |
9q33 |
NM_002160 |
|
Angiogenesis (n = 4)
|
|
|
|
IL8
|
|
Interleukin 8 |
4q13-q21 |
NM_000584 |
|
CXCL1
|
GRO1 |
Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
4q21 |
NM_001511 |
|
VEGF
|
VEGFA |
Vascular endothelial growth factor |
6p12 |
NM_003376 |
| PTGS2 |
COX2 |
Prostaglandin-endoperoxide synthetase 2 |
1q25.2-q25.3 |
NM_000963 |
|
Divers (n = 1)
|
| EGR1 |
|
Early growth response 1 |
5q31.1 |
NM_001964 |
