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Schematic representation of wound model. (A) Galiano's model. 6 mm round wounds were created on the mouse dorsum. The donut-shaped silicone sheet splint was centered on the wound, fixed with an immediate-bonding adhesive and interrupted nylon sutures. (B) Modified model used in our experiment. 15 mm wounds were made on the dorsal skin of mouse. A flexible plastic splint was fixed to the skin around the wound with an adhesive film and interrupted 6-0 nylon sutures.
