Table 2. Mammalian homologs of Drosophila pleated septate junction molecules.

Drosophila	Mammal
NeurexinIV	NCP1 (Nrx/Caspr1/Paranodin)
Coracle	Band4.1
Neuroglian	Neurofascin (NF155)
D-Contactin	Contactin
Sinuous, Megatrachea	Claudins (tight junction proteins)
Gliotactin	Neuroligin3
Discs Large	Dlg1-4
varicose	VAM-1/PALS2
Na/K ATPase subunits	Na/K ATPase subunits
Lachesin	IgLONs

The first four Drosophila pSJ molecules have been found in mammalian pSJs; the others have not. Sinous and Megatrachea are related to Claudins, molecules that have been found at tight junctions, the predominant paracellular barrier in mammals.