Table 1.
Illustration of input data and results of reported complete cases analysis versus baseline observation carried forward analysis in two example weight loss studies
| Example 1 | Example 2 | |||
|---|---|---|---|---|
|
n randomized Treatment |
59 | 57 | ||
|
n randomized Control |
59 | 50 | ||
|
n completed Treatment |
42 | 52 | ||
|
n completed Control |
41 | 47 | ||
| Mean(SD) Kg Change Treatment |
1.2(4.2) | 7.5(2.6) | ||
| Mean(SD) Kg Change Control |
−0.3(2.3) | 6.2(2.9) | ||
|
Complete
Cases analysis |
BOCF analysis |
Complete
Cases analysis |
BOCF analysis | |
| Total Unstandardized Treatment Effect |
1.500 | 1.063 | 1.300 | 1.014 |
| Variance of Weight Loss - Treatment |
17.64 | 12.77 | 6.76 | 10.67 |
| Variance of Weight Loss - Control |
5.29 | 3.67 | 8.41 | 10.07 |
| Variance of the Mean – Treatment |
0.42 | 0.22 | 0.13 | 0.19 |
| Variance of the Mean-Control |
0.13 | 0.06 | 0.18 | 0.20 |
| t(df), p |
t (81) = 2.024, p = 0.0462 |
t (116) = 2.013, p = 0.0464 |
t (97) = 2.339, p = 0.0214 |
t (105) = 1.623, p = 0.1076 |