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. 2011 Jun 17;3:203–211. doi: 10.2147/CLEP.S20247

Table 4.

c-statistics (area under ROC curve) as measure of discrimination between survivors and nonsurvivors (in-hospital, 30-day, and 1-year mortality)

Score/measure Outcome
c-statistic (95% CI)
In-hospital mortality 30-day mortality 1-year mortality
Mortality 83/469 (17.7%) 117/469 (24.9%) 178/469 (40.0%)
Charlson score 0.52 (0.46–0.59) 0.52 (0.46–0.57) 0.58 (0.53–0.63)
Charlson score, age and gender 0.64 (0.57–0.71) 0.65 (0.59–0.71) 0.65 (0.60–0.70)
Charlson score, age and gender, surgical/medical status 0.67 (0.60–0.7) 0.67 (0.61–0.73) 0.66 (0.61–0.71)
Charlson score, age and gender, surgical/medical status, social factors 0.68 (0.62–0.75) 0.70 (0.64–0.75) 0.68 (0.63–0.73)
Charlson score, age and gender, surgical/medical status, social factors, mechanical ventilation and renal replacement therapy 0.72 (0.65–0.78) 0.73 (0.68–0.78) 0.71 (0.67–0.76)
Charlson score, age and gender, surgical/medical status, social factors, mechanical ventilation and renal replacement therapy, primary diagnosis 0.75 (0.69–0.81) 0.75 (0.70–0.80) 0.72 (0.68–0.77)
Ten separate comorbidity groups* 0.59 (0.52–0.65) 0.58 (0.52–0.64) 0.63 (0.58–0.68)
Ten comorbidity groups,* with age, gender, surgical/medical status, social factors, mechanical ventilation and renal replacement therapy, primary diagnosis 0.75 (0.69–0.82) 0.76 (0.71–0.81) 0.75 (0.70–0.79)
SAPS II 0.74 (0.69–0.80) 0.72 (0.67–0.75) 0.70 (0.66–0.75)
SAPS III 0.69 (0.63–0.75) 0.68 (0.63–0.74) 0.69 (0.64–0.73)
APACHE II 0.73 (0.67–0.78) 0.71 (0.66–0.76) 0.71 (0.66–0.76)

Note:

*

See text for details.

Abbreviations: APACHE, acute physiology and chronic health evaluations; CI, confidence interval; ROC, receiver operating characteristic; SAPS, simplified acute physiology score.