Schematic diagram showing the likely locations on various cell types of membrane bound receptors and extracellular messengers which play a role in the control of contractility of prostatic smooth muscle. The diagrammatic representation is derived from experimental data obtained in a number of species. ACh, acetylcholine; ATP, adenosine 5′-triphosphate; CGRP, calcitonin gene-related peptide; ET, endothelin; NA, noradrenaline; NO, nitric oxide; SP, substance P.