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Ratio of kidney weight/body weight in mice treated with COX inhibitors. Treatment of mice with the indicated coxib or NSAID, at doses as shown in Table 1, was from P1 to P21. Following measurement of body weight, blood-free kidneys were removed and weighed. Data represent mean ± SEM of three independent experiments, *P < 0.05 versus control; #P < 0.05 versus celecoxib; §P < 0.05 versus valdecoxib.
