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. 2011 Jul;163(5):927–936. doi: 10.1111/j.1476-5381.2011.01313.x

Figure 5.

Figure 5

Impairment of postnatal renal development by treatment with coxibs and NSAIDs. COX inhibitors were given in the doses indicated in Table 1 from postnatal day P1 to P21. Thereafter kidneys were removed, fixed in PFA and histomorphometrically analysed. (A) Diameter of glomeruli, (B) subcapsular cortical thickness, (C) relative amount of superficial glomeruli within 58 µm from the renal cortical edge. Data represent mean ± SEM of three independent experiments, *P < 0.05 versus control; #P < 0.05 versus celecoxib; §P < 0.05 versus valdecoxib; &P < 0.05 versus coxibs.