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. 2011 Jul;163(5):948–963. doi: 10.1111/j.1476-5381.2011.01305.x

Figure 1.

Figure 1

Effect of chronic hypoxia and genetic deletion of Raf-1 kinase inhibitor protein (RKIP) on (A) mean systematic arterial pressure (SAP), (B) systolic right ventricular pressure (sRVP), (C) pulmonary vascular remodelling, (D) right ventricular hypertrophy RV/(LV + S) in mice and (E,F) the effect of RKIP deletion on phosphorylation of ERK1/2 (p-ERK1/2) in murine lungs (n = 4 to 10 mice in each group). *P < 0.05, **P < 0.01, ***P < 0.001, significantly greater than corresponding value in normoxic mice. †P < 0.05, ††P < 0.01, †††P < 0.001, significantly greater than corresponding value in wild-type (WT) mice. Data are shown as mean ± SEM.