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. 2011 Jul;163(5):984–994. doi: 10.1111/j.1476-5381.2011.01293.x

Figure 5.

Figure 5

SLIGRL-induced long-term depression (LTD) involves astrocytic and NMDA receptor activation. (A) SLIGRL (100 µM)-induced LTD was abolished by (DL)-AP5 and reduced by FAc pretreatment but unaffected by (S)-MCPG. (B) Input–output curves are unaffected by pretreatment with FAc (10 µM, 3 h). (C) DHPG (50 µM)-induced LTD did not occlude SLIGRL-induced LTD. (D) Summary of the effects of proteinase-activated receptor-2 activation in acute hippocampal slices. **P < 0.01, #P < 0.05 compared to SLIGRL alone, ##P < 0.01 compared to SLIGRL alone.