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. 2011 Jul;163(5):1034–1047. doi: 10.1111/j.1476-5381.2011.01301.x

Figure 9.

Figure 9

In (A), the effect of the GABAB antagonists CGP51176 and CGP36742 given in doses of 15 and 30 mg·kg−1 on (±)1-(2.5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-induced head twitches. In (B), the effect of GABAB receptor antagonist CGP51176 (B) and in (C) of CGP36742 on the inhibitory effects on GABAB receptor activators CGP44532 (0.250 mg·kg−1) and GS39783 (30 mg·kg−1) on DOI-induced head twitches in mice. All the compounds were administered 30 min before the test. Values represent the number of head twitches (mean ± SEM) during a 20 min session. **P < 0.001 versus vehicle-treated group; #P < 0.01 versus GS39783 or CGP44532 alone.