Skip to main content
. 2011 Jul;163(5):1034–1047. doi: 10.1111/j.1476-5381.2011.01301.x

Figure 10.

Figure 10

Suppression of the excitatory effect of (±)1-(2.5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) (10 µM) on the frequency of spontaneous EPSCs (sEPSCs) by CGP44532. (A) Examples of recordings from a representative neuron. (1) Baseline activity; (2) recording after 10 min incubation with DOI; (3) recording after 10 min incubation with by CGP 44532 (5 µM) in the presence of DOI. (B) Dose-dependent suppression of the effect of 10 µM DOI on the mean frequency (±SEM) of spontaneous EPSCs by CGP44532. *Significant difference between the effect of CGP44532 and that of DOI alone (5 µM: T = 2.35, P = 0.025, d.f. = 30; 10 µM: T = 4.19, P = 0.0002, d.f. = 30).