Table 1.

Age, family history of TGCT and tumor type in the discovery and replication sample sets

	Discovery			Replication
Status	Case		Control	Case		Control
Total	n = 349		n = 919	n = 439		n = 960
	n	%	n	n	%	n	%
Age [median, (interquartile range)]	31a (25, 39)		57 (52, 62)	33 (27, 38)		34 (30, 39)
Family history of TGCT
No	313	89.7	–	380	86.6	864	90.0
Yes	32a	9.2	–	11b	2.5	10b	1.0
Unknown	4	1.2	–	48	10.9	86	9.0
Personal history of cryptorchidism
No	310	88.8		394	89.8	942	98.1
Yes	35	10.0		42	9.6	18	1.9
Unknown	4	1.2		3	0.7	0	0
Tumor type
Seminoma	114	32.7	–	266	60.6	–	–
Non-seminoma	227	65.0	–	173	39.4	–	–
Unknown	8	2.3	–	0	0	–	–

TGCT, testicular germ cell tumor.

^aSixteen cases were recruited based on family history of TGCT. Among the non-selected (n = 333) cases, the proportion reporting any family history of TGCT was 4.8%.

^bReflects reported family history of TGCT among first-degree relatives only.