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. Author manuscript; available in PMC: 2011 Jul 7.
Published in final edited form as: Genet Med. 2010 Apr;12(4 Suppl):S155–S170. doi: 10.1097/GIM.0b013e3181d7acb0
Patent No. and Title Date
Filed/Issued
Inventors Assignee Claims
5705343, Method to Diagnose Hereditary Hemochromatosis Feb. 9, 1996 / Jan. 6, 1998 Drayna et al. Mercator Genetics Inc., Menlo Park, CA Mutation analysis of HFE with kit
5712098, Hereditary Hemochromatosis Diagnostic Markers and Diagnostic Methods Apr. 16, 1996/ Jan. 27, 1998 Tsuchihashi et al. Mercator Genetics, Menlo Park, CA Mutation analysis for HFE
5753438, Method to Diagnose Hereditary Hemochromatosis May 8, 1995 / May 19, 1998 Drayna et al. Mercator Genetics Inc., Menlo Park, CA Method for diagnosing the mutation of an HFE sequence; mutation sequences, but not the whole gene.
6025130, Hereditary Hemochromatosis Gene May 23, 1996 / Feb. 15, 2000 Thomas et al. Mercator Genetics Inc., Menlo Park, CA HFE gene and a diagnostic method; whole HFE gene sequence
6140305, Hereditary Hemochromatosis Gene Products Apr. 4, 1997 / Oct. 31, 2000 Thomas et al. Bio-Rad Laboratories, Inc., Hercules, CA Polypeptides associated with HFE
6228594, Method for Determining the Presence or Absence of Hereditary Hemochromatosis Gene Mutation Feb. 14, 2000 / May 8, 2001 Thomas et al. Bio-Rab Laboratories, Hercules, CA Diagnostic method for C282Y and H63D detection using DNA and RNA.
6355425, Mutations Associated With Iron Disorders Mar. 26, 1999 / Mar. 12, 2002 Rothenberg et al. Billups-Rothenberg, Inc., San Diego, CA Diagnostic method for a panel of mutations in HFE, including : S65C, 193T, G93R, 277C, 105T, 314C
6762293, Diagnostics and Therapeutics for Autosomal Dominant Hemochromatosis Oct. 10, 2001 / Jul, 13, 2004 van Duijn et al. Erasmus University Rotterdam, Rotterdam (NL) Ferroportin (SLC11A3) sequence and method of diagnosis for SLC11A3
6849399, Methods and Compositions for Diagnosis and Treatment of Iron Misregulation Diseases Aug. 27, 1997 / Feb. 1, 2005 Feder et al. Bio-Rab Laboratories, Hercules, CA Diagnostic method for transferring receptor (TFR2) and mutation A424G
6955875, Mutations associated with iron disorders Oct. 16, 2001/ Oct. 18, 2005 Rothberg et al. Billups-othberg Inc. Methods for diagnosing HFE by detecting mutations in nucleotide position 193
7067255, Hereditary Hemochromatosis Gene May 2, 2002 / Jun 27, 2006 Thomas et al. Bio-Rab Laboratories, Hercules, CA Method for detecting three mutant alleles (24d1, 2 and 7)
7078513, Plasmids Comprising Nucleic Acids from the Hereditary Hemochromatosis Gene Feb. 4, 2000 / Jul. 18, 2006 Thomas et al. Bio-Rab Laboratories, Hercules, CA Plasmid containing HFE mutation 24d1
7026116, Polymorphisms in the Region of the Human Hemochromatosis Gene May 7, 1997 / Apr. 11, 2006 Ruddy et al. Bio-Rad Laboratories, Hercules, CA Isolated polynucleotide of HFE gene sequence containing SNP variants, and a kit.