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. 2011 Jun 23;8:15. doi: 10.1186/1476-9255-8-15

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Copyright ©2011 Abdelsamed et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Increased collagen in lungs of T-bet mice exposed to S. rectivirgula . C57BL/6 or T-bet^-/-mice (5/group) were intranasally exposed to S. rectivirgula (150 μg) or saline for 3 weeks. The right lung lobe was removed from mice and the collagen content was determined as described in methods. The results are expressed as amount of collagen/right lung lobe and represent the average+/- SD in each group of mice. *p < 0.05; T-bet KO mice exposed to S. rectivirgula compared to WT mice exposed to S. rectivirgula.