Table 1.
Study demographics
| Group I (Natural cycle) | Group II (letrozole 2.5 mg) | Group III (letrozole 5 mg) | P value | |
|---|---|---|---|---|
| Total No of patients | 47 | 125 | 36 | |
| Age (Mean ± SD) | 34.8 ± 5.03 | 33.5 ± 4.02 | 33.88 ± 3.45 | NS |
| Day 3 FSH (IU/L) | 6.01 ± 1.71 | 6.47 ± 2.16 | 7.49 ± 3.76 | I Vs II: 0.233 I Vs III: 0.033 |
| Total No of cycles started | 71 | 179 | 50 | |
| Completed cycle: No, [%] | 63 [88.7] | 142 [79.3] | 43 [86] | |
| Total number of cycles cancelled: No, [%] | 8 [11.3] | 37 [20.7] | 7 [14] | 0,06 |
| No of monitoring visits (Mean ±SD) | 2.08 ± 1.02 | 2.3 ± 1.12 | 2.68 ± 1.11 | I Vs II: 0.232 I Vs III: 0.003 |
| Causes of cycle cancelling | ||||
| Poor responder: No, [%] | 5 [62.5] | 9 [24.3] | 0 [0] | NS |
| Ovarian cyst: No, [%] | 0 [0] | 16 [43.2] | 2 [28.6] | NS |
| Patient request: No, [%] | 1 [12.5] | 8 [21.6] | 0 [0] | NS |
| Elevated FSH: No, [%] | 0 [0] | 2 [5.4] | 3 [42.9] | NS |
| Others: No, [%] | 2 [25] | 2 [5.4] | 2 [28.6] | NS |
| Indication for IUI | ||||
| Male factor infertility: No, [%] | 38/71 [53.5] | 55/179 [30.7] | 19/50 [38] | NS |
| Unexplained infertility: No, [%] | 33/71 [46.5] | 106/179 [59.3] | 30/50 [60] | NS |
| Endometriosis: No, [%] | 0 [0] | 9/179 [5] | 0 [0] | NS |
| Others No, [%] | 1/71 [1.4] | 9/179 [5] | 1 [2] | NS |