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. 2011 Jul 7;7(7):e1002091. doi: 10.1371/journal.pgen.1002091

Figure 4. Decreased TNIP1 expression in SSc patients.

Figure 4

(A) Expression of the TNIP1 protein was decreased ex vivo in SSc lesional skin tissue compared to controls (arrows indicate TNIP-1 positive cells). Shown are representative sections of the 5 patients and controls included in the analysis. (B) Consistent with these findings, a 1.7-fold decrease of TNIP1 mRNA levels was observed in dermal fibroblasts from SSc patients (* indicates a P-value = 0.001 vs. controls). These results were confirmed at the protein level (C).