Table 1. The demographic and clinical characteristics of subjects.

Parameters	Immune-active (IA)	Immune-tolerant (IT)	Healthy controls
NO.	23	13	12
Age (years)
Mean ± SD	42.9±8.1	40.8±6.7	35.75±12.35
Median (range)	45 (30–61)	38 (30–58)	35 (23–50)
Sex N (%)
Male	19 (83)	9 (69)	9 (75)
Female	4 (17)	4 (31)	3 (25)
HBV DNA (log10 copies/ml)
Median (range)	4.8* (3.5–6.8)	6.9 (5.2–7.5)	NA
ALT (U/L)
Median (range)	135* (46–2343)	30 (17–40)	15 (5–20)
AST (U/L)
Median (range)	104.5* (24–876)	24 (21–39)	11 (9–25)

Normal values: ALT≤40 IU/L; AST≤40 IU/L; HBV DNA ≤3 log10 copies/ml;

*P<0.05 vs. IA patients.