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. 2001 Apr 15;29(8):1695–1702. doi: 10.1093/nar/29.8.1695

Figure 1.

Figure 1

Domains of hMLH1 interacting with hMLH3, hPMS1 and hPMS2. The β-gal activities in yeast cells containing various lexA DNA BD and VP16 transcriptional AD plasmids. The left figure represents schematic diagrams of the full-length (residues 1–756) and the 15 hMLH1 deletion constructs in AD plasmids. Lane hMLH3, hPMS1 or hPMS2 indicates the β-gal activities of yeast cells that contain the full-length hMLH3, hPMS1 or hPMS2 BD plasmid and the corresponding truncated hMLH1 AD plasmid. The mean and SD of three independent transformants are shown. The mean β-gal activities in yeast cells containing only hMLH3, hPMS1 or hPMS2 BD plasmid are 0.3, 0.1 or 0.1 U, respectively.