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. 2011 Jul 7;6(7):e21979. doi: 10.1371/journal.pone.0021979

Figure 1. Identification and characterization of Lampe1 ENU germline mutants.

Figure 1

(a) Reduced growth of homozygote Lampe1 male and female mice compared to heterozygote littermates. (b) Relative liver weight in homozygote/heterozygote Lampe1 mutants and wildtype C57BL/6J mice. (c) Macroscopic view of livers from 10-week-old homozygote/heterozygote Lampe1 mutants and C57BL/6J wildtype mice. (d–f) Blood levels of ALT, AP and AST liver enzymes measured in 10-week-old Lampe1 homozygote/heterozygote mutants and C57BL/6J mice. All experiments were performed using at least n = 3 per group. *** = P<0.001.