Table 3. Association between the ESR1 (6q25) locus and pQCT BMD.

SNP	Chr position	Base change	MAF	Midshaft radius cortical density		Distal radius trabecular density
				β (95%CI)	p-value	β (95%CI)	p-value
rs9479055	151889660	A→C	0.41	−0.13 (−0.24, −0.01)	0.028	−0.07 (−0.19, 0.05)	0.266
rs4463269	151903921	C→T	0.30	−0.04 (−0.16, 0.09)	0.531	−0.01 (−0.14, 0.12)	0.890
rs3757317	151907224	C→T	0.15	−0.12 (−0.27, 0.03)	0.119	−0.05 (−0.21, 0.11)	0.562
rs4869738	151933844	G→T	0.24	−0.01 (−0.14, 0.13)	0.917	0.01 (−0.13, 0.15)	0.881
rs4870044	151943102	C→T	0.28	−0.19 (−0.31, −0.07)	0.002	−0.12 (−0.24, 0.01)	0.065
rs1038304	151974868	A→G	0.49	−0.03 (−0.14, 0.08)	0.604	−0.14 (−0.25, −0.03)	0.016
rs6929137	151978370	G→A	0.31	−0.01 (−0.13, 0.11)	0.842	−0.08 (−0.20, 0.04)	0.206
rs1999805	152110057	T→C	0.41	−0.08 (−0.19, 0.03)	0.148	−0.18 (−0.29, −0.06)	0.003

β, effect estimates are shown as standardized values (standard deviations above or below the population average) for each copy of the minor allele adjusted for height and weight.