Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Jul 7;7(7):e1002089. doi: 10.1371/journal.pcbi.1002089

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

PMC Copyright notice

A) Calculus of variation waveforms determined from an optimization of the V, m, n, and h values at the end of the depolarizing (blue curve) and hyperpolarizing (green curve) pulses used to elicit a spike in the Hodgkin & Huxley model (Figure 2B & C, respectively) as described in the text (Results and Methods). These results were normalized relative to the maximum value of the blue curve. The RMS current of the blue curve is 38% less than that of the green curve. B) Overlap of the blue curve in A with the optimal noise trace obtained from the analysis of Figure 3. C) Comparison of another one of the results from Figure 4 with the optimal calculus of variations stimulus determined from a revised version of the Hodgkin & Huxley equations [14].