Reflectance confocal microscopy of a human subject at 24 h post-injury showing (a) normal skin, with dermal capillaries manifested as black punctuate areas within dermal papillae (white rings), (b) superficial burn, with apparent enlargement of the dermal capillaries secondary to edema, (c) superficial partial-thickness burn, showing incomplete destruction of the dermal papillae, and (d) deep partial-thickness burn, showing complete destruction of the papillae. (Reprinted from Ref. [47]. Copyright 2009 by Elsevier. Reprinted with permission.)