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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Clin Cancer Res. 2011 May 12;17(13):4309–4319. doi: 10.1158/1078-0432.CCR-10-1820

Figure 5. Silencing of MAGE-A results in repression of survivin in the absence of p53.

Figure 5

ARP-1 (p53-/-) and Pt #1 (p53mut/-) cells were transduced with MAGE-A-targeted (shMA) shRNA lentiviral constructs or controls as indicated and cells were harvested at 48 hrs (Pt #1) or 72 hrs (ARP-1). A. p53 protein in Pt #1 cells was assessed by western blot. B. Bax, Bak, and survivin mRNA expression was assessed by qRT-PCR. C. Protein expression of Bax, Bak, and survivin was assessed by western blot.