Table 1.
Newly diagnosed n=46 | Relapsed n=35 | |
---|---|---|
Age | 62.0 ± 1.5 yrs | 57.7 ± 1.5 yrs |
Sex | M = 27, F = 19 | M = 20, F = 15 |
Heavy chain isotype | IgG = 26 IgA = 10 IgM = 1 IgG + IgA = 1 Light chain only = 8 |
IgG = 18 IgA = 3 IgM = 1 IgD = 1 Light chain only = 7 Oligosecretory = 4 |
Light chain isotype | Kappa = 31 Lambda = 15 |
Kappa = 23 Lambda = 11 Not done = 1 |
Cytogenetics | Normal = 32 Del(20q) = 1 Inv(2) = 1 Inv(9) = 2 Y(-) = 2 Complex t(1;8); t(11;14); t(12;27) = 1 Not done = 7 |
Normal = 18 Complex = 7 Complex incl. t(5;13)(q31;q14) = 1 Inv(9) =1 Not done = 8 |
FISH | Normal = 15 Del (13q14) = 4 Complex incl. del(13q14) = 7 t(11;14) = 4 t(4;14) = 1 Trisomy/ tetrasomy 11 = 5 Trisomy 11/ trisomy 17 = 1 Complex = 1 Not done = 8 |
Normal = 19 t(11;14) =2 Del(13) = 2 Trisomy 11 = 1 Trisomy 11 + del(13q14) = 1 Complex = 1 Not done = 9 |
Serum β2-microglobulin | 4.8 ± 0.6 mg/ dL | 4.7 ± 0.7 mg/ dL |
Serum albumin | 3.6 ± 0.1 mg/ dL | 3.5 ± 0.1 mg/ dL |
Hemoglobin | 10.4 ± 0.4 gm/ dL | 10.2 ± 0.3 gm/ dL |
Serum creatinine | 1.5 ± 0.2 mg/ dL | 2.2 ± 0.4 mg/ dL |