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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Cancer Prev Res (Phila). 2011 May 10;4(7):1061–1072. doi: 10.1158/1940-6207.CAPR-11-0006

Figure 3.

Figure 3

Figure 3a. Volcano plot of p-values versus effect size in the expression arrays. The log10 of the Fold Change P value of tumor vs. control from the 9,441 upregulated genes are plotted to the right of the 0 effect size value in center and log10 of the Fold Change P value of tumor vs. control from the 8,356 downregulated genes are plotted to the left. The 301 significantly hyper methylated genes in OSCC are in red: 140 genes are plotted to the left and 161 are plotted to the right of ) effect size in the center. The Y axis represents the log10 of the Fold Change P value of tumor vs. control. The X axis represents the log2 fold change of tumor vs. control. Figure 3b. A Venn diagram shows the overlapping 140 genes, significantly hypermethylated in the methylation platforms and significantly downregulated in the expression arrays.