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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Alcohol Clin Exp Res. 2011 Apr 4;35(8):1509–1518. doi: 10.1111/j.1530-0277.2011.01487.x

Figure 5. TLR4 induces CC-chemokines in BM-derived cells and endogenous liver cells in alcoholic liver disease.

Figure 5

(A-D) The TLR4-chimeric mice [WT mice with WT BM (n=9); TLR4-/- mice with WT BM (n=6); WT mice with TLR4-/- BM (n=7); TLR4-/- mice with TLR4-/- BM (n=6)] were treated with intragastric ethanol feeding for 4 weeks. Hepatic mRNA levels of CCL2 (A), CCL3 (B), CCL4 (C) and CCL5 (D) were measure by qPCR and are expressed as fold change compared with corresponding pair-fed mice. Values with different letters are significantly different, p<0.05.