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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Melanoma Res. 2011 Aug;21(4):285–297. doi: 10.1097/CMR.0b013e32834495c3

Fig. 2.

Fig. 2

Distribution in functional categories of genes regulated by PEDF in A375 melanoma cells. (a) Heat map of expression of genes regulated by PEDF in two independent hybridizations (Hybr. 1 and Hybr. 2) of A375-pCEP4-PEDF Pool cells compared to control A375-pCEP4 Pool cells. Coloring represents normalized signal intensity of the ratio log2 (A375-pCEP4-PEDF Pool/A375-pCEP4 Pool): red, upregulation; black, no change; green, downregulation. (b) Diagram showing genes regulated by PEDF grouped into biological processes and/or functional categories as described in the main text. Percentage of regulated genes in each category relative to total number of regulated genes is shown. For some categories the most relevant genes are listed in the lower boxes, being shown in red when upregulated and in green when downregulated in A375-pCEP4-PEDF Pool compared to A375-pCEP4 Pool.