Table 2.

Targets identified by integrative approach and validation

Gene	Abbreviation	Location	CGH Loss %	Median Tumor Expression vs Nevi	Aza Fold Upregulation
Chordin-like 1	CHRDL1	Xq23	−13.2	0.15	1.70
Secreted frizzled-related protein 1	SFRP1	8p12	−12.3	0.17	1.72
Transmembrane protein 47	TMEM47	Xp11	−13.5	0.08	1.29
Transcription factor 8	ZEB1	10p11	−20.8	0.33	1.85
Lipoprotein lipase	LPL	8p22	−13.2	0.32	1.28
Retinoic acid receptor responder 1	RARRES1	3q25	−19.8	0.46	1.74
Phosphatidylinositol-specific phospholipase C, X domain containing 1	PLCXD1	Xp22	−16	0.41	1.32
Zinc finger protein 22	KOX 15	10q11	−24.5	0.43	1.29