Table 2.
EC50s of AMPs against P. aeruginosa.
Anti-microbial peptide | Molecular weight (g/mol) | EC50 (μg/ml) | 95% CI | EC50 (µM) |
---|---|---|---|---|
NA-CATH | 5885.5 | 0.52 | 0.39–0.69 | 0.09 |
NA-CATH:ATRA1-ATRA1 | 5977.6 | 0.37 | 0.21–0.63 | 0.06 |
ATRA-1 | 2409.06 | 0.64 | 0.52–0.79 | 0.27 |
ATRA-2 | 2316.96 | 62.8 | 27.7–949 | 27.1 |
LL-37 | 5177.42 | 0.47 | 0.28–0.78 | 0.09 |
D-LL-37 | 5177.42 | 0.72 | 0.37–1.36 | 0.14 |
This table indicates the EC50 of the peptides against P. aeruginosa in an anti-microbial assay. The molecular weight reported here for each peptide reflects the TFA salts of the peptides. These molecular weights were then used to convert the EC50 in μg/ml to μM, to enable comparisons on a molecule-by-molecule basis.