Table 3.

Pseudomonas aeruginosa genes downregulated in the presence of D- or L-LL-37.

Treatment	Identification	Protein	Designation	Fold change	p-value
L-LL-37 (1 μg/ml)	PA3478	Rhamnosyltransferase chain B	rhIB	−8.4	2.73E-02
L-LL-37 (1 μg/ml)	PA3479	Rhamnosyltransferase chain A	rhIA	−4.5	6.36E-03
D-LL-37 (1 μg/ml)	PA3478	Rhamnosyltransferase chain B	rhIB	−7.2	6.50E-04
D-LL-37 (1 μg/ml)	PA3479	Rhamnosyltransferase chain A	rhIA	−3.0	4.11E-06

This table indicates the fold change (relative to the control) in regulation of P. aeruginosa genes rhlA and rhlB in the presence of 1 μg/ml of either D- or L-LL-37 in biofilm. The relative levels of transcription was normalized by correcting for rpoD transcription levels.