Table 1.
Needle-tip proteins of type III secretion system.
| No. of residues | Global alignmenta with PcrV identity (similarity) | GenBank accession no. | ||
|---|---|---|---|---|
| V-tip protein (Ysc family) | ||||
| PcrV | Pseudomonas aeruginosa | 294 | Strain PA103, ours | |
| LcrV | Yersinia spp. | 326 | 36.4% (64.4%) | P23994 |
| AcrV | Aeromonas spp. | 361 | 34.2% (59.8%) | YP_001144289 |
| Vp1659 | Vibrio parahaemolyticus | 607 | 35.3%b (55.7%b) | NP_798038 |
| Tip protein containing a chaperone domain (Inv-Mxi-Spa family) | ||||
| IpaD | Shigella flexneri | 332 | 18.2% | AAL72350 |
| SipD | Salmonella spp. | 343 | 20.4% | ACY89896 |
| BipD | Burkholderiapseudomallei | 310 | 21.6% | EET03029 |
| CT584 | Chlamydiatrachomatis | 183 | 16.4% | NP_220099 |
| Filamentous-tip protein (EC family) | ||||
| EspA | EPEC/EHECc | 192 | 17.0% | ACG59618 |
| Bsp22 | Bordetella spp. | 205 | 17.3% | CAE32114 |
aAnalyzed by using ALIGN © 1997 by William R. Pearson and the University of Virginia). bResidues 420-607 of Vp1659 were used for alignment.cEPEC: enteropathogenic E. coli; EHEC: enterohemorrhagic E. coli.